Evaluation of confocal laser endomicroscopy to improve the diagnosis of IBS

June 14, 2021

Irritable bowel syndrome (IBS) affects 10-15% of the world‘s population. However, it has been demonstrated that there are often defined pathophysiologies behind this diagnosis, they are simply not correctly detected by standard diagnostics and therefore prevents effective and targeted therapy.

The use of microscopic imaging of the small intestinal mucosa by confocal laser endomicroscopy allows us to gain first-time insights into the function of the intestinal barrier and allows us to identify previously unknown diseases. For example, patients pre-diagnosed with IBS often have atypical food allergies or leaky gut syndrome. Accordingly, the therapeutic measures taken on the basis of these findings are specific, and the continuous improvement of these measures, whether through optimization of the diet or the targeted use of supplements and pharmaceuticals, is the overriding goal of our efforts.

CLE diagnostics is operated by INUM together with the clinical section of nutritional medicine, medical department 1, university hospital of Schleswig-Holstein, campus Lübeck.